Heat Shock 105kDa/110kDa Protein 1 (HSPH1) (Middle Region) Peptide
HSPH1
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN5511971
Aperçu rapide pour Heat Shock 105kDa/110kDa Protein 1 (HSPH1) (Middle Region) Peptide (ABIN5511971)
Antigène
HSPH1
(Heat Shock 105kDa/110kDa Protein 1 (HSPH1))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Séquence
- ADKANEKKVD QPPEAKKPKI KVVNVELPIE ANLVWQLGKD LLNMYIETEG
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti- HSPH1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HSPH1 (Heat Shock 105kDa/110kDa Protein 1 (HSPH1))
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Sujet
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Acts as a nucleotide-exchange factor (NEF) for chaperone proteins HSPA1A and HSPA1B, promoting the release of ADP from HSPA1A/B thereby triggering client/substrate protein release. Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities.
Alias Symbols: HSP105, HSP105A, HSP105B, NY-CO-25
Protein Size: 858 -
ID gène
- 10808
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NCBI Accession
- NM_001286503, NP_001273432
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UniProt
- Q92598
Antigène
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